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Clin Exp Dermatol ; 31(1): 1-5, 2006 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-16309468

RESUMO

As one of the most important vesicant agents, the destructive properties of mustards on the skin, eyes and respiratory system, combined with a lack of antidote, makes them effective weapons. Such weapons are inexpensive, easily obtainable and frequently stockpiled. Sulphur mustard (mustard gas) has been used as a chemical warfare agent in at least 10 conflicts. In this article, the use of mustard as a potential agent of chemical warfare and terrorism is outlined. The dose-dependent effects of acute sulphur mustard exposure on the skin, eyes, and respiratory system are described, as well as the possible extents of injuries, the mechanisms of action and the long-term complications. Prevention and management of mustard exposure are briefly discussed. The need for awareness and preparedness in the dermatological community regarding mustard exposure is emphasized.


Assuntos
Terrorismo Químico , Substâncias para a Guerra Química/toxicidade , Fármacos Dermatológicos/toxicidade , Compostos de Mostarda/toxicidade , Adulto , Terrorismo Químico/prevenção & controle , Criança , Relação Dose-Resposta a Droga , Humanos , Compostos de Mostarda/administração & dosagem , Gás de Mostarda/administração & dosagem , Gás de Mostarda/toxicidade , Compostos de Mostarda Nitrogenada/toxicidade , Pele/efeitos dos fármacos , Dermatopatias/prevenção & controle , Fatores de Tempo
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